Mixed acinar-endocrine carcinoma (MAEC) of the pancreas is a rare neoplasm, consisting of at least 25%â??30% of acinar and\nneuroendocrine populations. Patients are often middle-aged and present with nonspecific symptoms. Imaging typically reveals a\nsolid lesion in the pancreatic head. Management involves surgical resection and the overall prognosis is variable. Here, we present\na case of a 48-year-old male who presented with a MAEC arising from duodenal pancreatic heterotopia. This is the one of the first\ncases, with histologic evidence, of MAEC arising from pancreatic heterotopia.
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